Factors such as inadequate funds, lack of infrastructural facilities, lack of experience, and multiple taxation have been reported to contribute to the failure of SMEs. More recently, enterprises in the streets of Abuja, Nigeria, have been characterised by unsustainable success and high failure rates. This is amidst the stenches and eyesores that the indiscriminately dumped wastes from their entrepreneurial activities and customers’ consumption patterns constitute. Consequently, owing to the reiteration of the need for responsible business practices and responsible consumption by the SDGs and the commonplaceness of micropreneurships in Abuja, this study seeks to investigate the mediating effects of irresponsible entrepreneurship practices (IEP) and irresponsible consumption patterns (ICP) on the relationship between micro-preneurship activities (MPA) and unsustainable entrepreneurial success (UES). To test the research hypotheses, a cross-sectional research design, criterion sampling, proportionate stratified random sampling, and simple random sampling techniques were employed to generate data from 1420 micropreneurs and customers. The results of the 2-way parallel mediation analysis show that the direct and total effects of MPA on UES are positive and significant; MPA directly and positively influenced IEP and ICP. In contrast, the direct effects of IEP and ICP on UES are positive and significant. Further, the indirect effect of MPA on UES through IEP and ICP is significant and positive. Thus, based on the MPA, IEP, ICP, and UES insights, the study extends the literature in these areas. Again, the results can influence both the practitioners and policymakers to craft mechanisms that will facilitate the emergence of responsible entrepreneurship and consumption practices and the achievement of the SDGs.