Candida has been reported has one of the most prevailing yeast genera. Candida is of diverse species that are commonly found in soil and in the mucosal surfaces of genitourinary tract, gastrointestinal tract, and human mouth cavity human with ability to cause oral thrush or vaginal thrush. The incidence of Candida infections has dramatically increased in recent years due to a significant increase in cases like HIV/AIDS, cancer, diabetes mellitus, long time use of antibiotic and tissue transplant. It is a cross-sectional study involving patients diagnosed of Candidiasis. The aim of this study is to identify, characterize and determine the prevalence of Candida species isolated from clinical specimens in selected health care facilities in Ilorin, Kwara state, Nigeria using conventional methods with CHROM agar Candida differential media and Germ tube test. Of the 232 isolates recovered from Sabouraud dextrose agar, sub-cultured on CHROM agar and tested for Germ Tube Test. C. albicans 131(56.5%), has the highest prevalence, non-albicans such as C. tropicalis has the prevalence of 36(15.5%), C. dubliniensis 27(11.6%), C. glabrata 14(6.0%), C. krusei 12(5.2%), there was mixed growth 7(3.0%) and 3(1.3%) did not grow on CHROM agar. Candida albicans (56.5%) is the most prevalence of Candida species isolated from clinical cases and most prevalence in Female (59.6%) while C. tropicalis has the highest prevalence in Male (36.8). Age group between 20 -29 has the higher prevalence (64.5%) compared to to other age groups. Clinical cases with highest number of Candida species was High Vaginal infection (58.2%) and pelvic inflammatory disease (34.1%) and female subjects with higher prevalence of Candida infections (91.8%) compared to male (8.2%). The use of CHROM agar provided a rapid and inexpensive method for speciation of Candida species from clinical cases and suitable for routine diagnosis of Candidiasis.
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