@article{Mordi_2015, title={The involvement of free radicals in the mechanism of -Carotene Degradation}, volume={3}, url={https://journals.covenantuniversity.edu.ng/index.php/cjpls/article/view/154}, abstractNote={<p>-Carotene, a pro-vitamin A carotenoid, was reacted with oxygen in benzene<br />as solvent, in the dark. The products of oxidation were characterised by HPLC with a<br />UV photodiode detector and LC-MS, EI mode. The products identified were oxygencontaining<br />compounds of the type epoxides, aldehydes and ketones. ESR study of<br />retinyl- and ionyl-derivatives revealed that the secondary sites C7 and C9 were the most<br />reactive towards radical generation. Both the results of product analysis and the ESR<br />study enabled us to propose that the products of -carotene autoxidation were obtained<br />by a free radical mechanism involving initial formation of a biradical during the transto-<br />cis isomerisation at the 15,15’ bond and attack by oxygen.<br />Keywords: Carotene, Carotenoids, Apo-carotenoids, ESR, Degradation, Autoxidation,<br />Free radicals.</p>}, number={1}, journal={Covenant Journal of Physical and Life Sciences}, author={Mordi, Raphael C.}, year={2015}, month={Jun.} }